The Effects of Protein Source on Appetite Control, Satiety, and Subsequent Food Intake
Completed · Not applicable
Conditions studied: Appetitive Behavior
In brief
The investigators propose a randomized, tightly-controlled breakfast trial in normal to overweight adults that will test whether the consumption of various types of protein-rich meals, containing \~24g of protein, will differentially alter food intake and meal initiation through proposed appetite and satiety mechanisms. Aim 1: To examine whether the consumption of protein-rich meals that vary in protein quality (source) effect: 1. postprandial feelings of hunger, fullness, desire to eat, prospective food consumption 2. postprandial fluctuations in key appetite and satiety hormones 3. eating initiation (i.e., motivation to eat (again)) 4. food cravings Aim 2: To examine whether the consumption of protein-rich meals that vary in protein quality (source) effect: 1. energy intake and food choice within the breakfast meal 2. energy intake and food choice at the next eating occasion 3. energy intake and food choice across the entire day
Key facts
- Study ID
- NCT03154606
- Run by
- Purdue University
- People needed
- 35
- Starts
- 2017-03-21
- Expected to finish
- 2018-07-27
- Last updated by the study team
- 2019-05-02
Who can join
Age: 20 and older, up to 40. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Males and females
- All ethnicities
- Age: 20-40y
- BMI/BMI Percentile: 18.5-29.9 kg/m2
- Consumes breakfast (>110 kcal prior to 10 am) at least 5 days/week for the past year
- Never smoked or used other tobacco products
- Willing to consume the study breakfasts
- Generally healthy (as assessed by Medical History Questionnaire)
- Health conscious as determined by answering yes to 3 pre-screening health \& lifestyle questions
- Rating of ≥ 5 illustrating a minimum of "neither like nor dislike on a hedonic 9 pt taste test of all testing treatments
You may not qualify if…
- Clinically diagnosed with an eating disorder
- Metabolic, hormonal, and/or neural conditions/diseases that influence metabolism or appetite
- Currently or previously on a weight loss or other special diet (in the past 6 months)
- Gained/lost ≥4.5kg over the past 6 months
- Donated (or plan to donate) blood through the American Red Cross within the past 6 months (or future 6 months)
- Taking medication that would directly influence appetite (weight-loss drugs or antidepressant, steroid, or thyroid medication, unless dosage has been stable for at least 6 months)
- Not willing or able to complete all study testing procedures
- Clinically diagnosed with a sleeping disorder
Where it is running
- Purdue University — West Lafayette, Indiana, United States
Full record on ClinicalTrials.gov
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