Effects of Progressive Intensity Exercise Training on Glycemic Control in Older Adults
Completed · Not applicable
Conditions studied: PreDiabetes, Aging
In brief
The purpose of this study is to compare the effects of moderate versus vigorous intensity exercise training on glycemic control in older adults. Glycemic control will be assessed using an oral glucose tolerance test and continuous glucose monitors. In addition, the investigaotrs will investigate whether engaging in an exercise training program elicits changes in sedentary behavior, non-exercise physical activity, sleep, and total daily energy expenditure.
Key facts
- Study ID
- NCT03154073
- Run by
- University of Colorado, Denver
- People needed
- 20
- Starts
- 2017-07-20
- Expected to finish
- 2019-12-13
- Last updated by the study team
- 2021-07-08
Who can join
Age: 60 and older, up to 79. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age ≥60 to <80 years upon study entry
- Body mass index ≥25.0 to <35.0 kg/m2 as measured at the baseline screening visit
- HBA1c ≥ 5.7% to <6.5% OR Fasting Glucose ≥ 100 to <126 mg/dl as measured at the baseline screening visit.
You may not qualify if…
- History of metabolic, cardiac, or pulmonary disease that classifies the individual as high risk by the American College of Sports Medicine
- Participants with un-controlled hypertension and un-controlled thyroid disorders and are on medication for <3 months.
- Resting systolic blood pressure >160 mmHg or resting diastolic blood pressure >100 mmHg will be exclusionary. At the baseline screening visit, an initial resting blood pressure measurement will be attained after the participant is seated at rest for 5 minutes. Subsequent resting blood pressure measurements can be taken at the baseline screening visit up to 3 times to determine eligibility. Subsequent measurements will be taken under the same conditions as the initial measurement with a minimum of 5 minutes between readings. If more than one reading is needed to determine eligibility, the average of all readings taken will be used.
- Thyroid dysfunction, defined as an ultrasensitive thyroid stimulating hormone (TSH) <0.5 or >5.0 mU/L; volunteers with abnormal TSH values will be re-considered for participation in the study after follow-up evaluation by the PCP with initiation or adjustment of thyroid hormone replacement.
- Self-reported chronic Inflammatory Disease (e.g., rheumatoid arthritis, lupus)
- Currently taking statins, hormone replacement therapy, prescribed sleep medications, or medications that may affect heart rate response to exercise (e.g., beta blockers)
- Participating in >30 minutes of aerobic exercise/week during the past 3 months
- Inability to complete exercise test
- Sleep Apnea
Where it is running
- University of Colorado Anschutz Medical Campus — Aurora, Colorado, United States
Full record on ClinicalTrials.gov
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