A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma
Completed · Phase 1/Phase 2
Conditions studied: Brain and Central Nervous System Tumors
In brief
The primary objective of this study is to evaluate the safety, efficacy and clinical activity of Pamiparib in combination with radiation therapy (RT) and/or temozolomide (TMZ) in participants with newly diagnosed or recurrent/refractory glioblastoma.
Key facts
- Study ID
- NCT03150862
- Run by
- BeiGene USA, Inc.
- People needed
- 116
- Starts
- 2017-07-24
- Expected to finish
- 2021-03-17
- Last updated by the study team
- 2025-02-04
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Center For Neurosciences — Tucson, Arizona, United States
- UCLA — Los Angeles, California, United States
- University of California At San Francisco — San Francisco, California, United States
- Sarah Cannon Research Institute (Scri) At Health One — Denver, Colorado, United States
- Massachusetts General Hospital — Boston, Massachusetts, United States
- Dana Farber Cancer Institute — Boston, Massachusetts, United States
- Henry Ford Hospital — Detroit, Michigan, United States
- Midamerica Division, Inc — Kansas City, Missouri, United States
- Washington University in St Louis — St Louis, Missouri, United States
- Memorial Sloan Kettering Cancer Center Mskcc — New York, New York, United States
- Cleveland Clinic Foundation — Cleveland, Ohio, United States
- Ohio State University — Columbus, Ohio, United States
- Sarah Cannon Research Institute (Scri) Stephenson Cancer Center — Oklahoma City, Oklahoma, United States
- Penn State Milton S Hershey Medical Center — Hershey, Pennsylvania, United States
- Thomas Jefferson University Hospital Jefferson Health — Philadelphia, Pennsylvania, United States
- Tennessee Oncology, Pllc Nashville — Nashville, Tennessee, United States
- Huntsman Cancer Institute — Salt Lake City, Utah, United States
- University of Virginia — Charlottesville, Virginia, United States
- Liverpool Hospital — Liverpool, New South Wales, Australia
- Institut Gustave Roussy — Villejuif, France
- Universitair Medisch Centrum Utrecht — Utrecht, Netherlands
- University of Zurich Medical School — Zurich, Switzerland
Full record on ClinicalTrials.gov
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