Connecting Youth and Young Adults to Optimize ART Adherence: YouTHrive Efficacy Trial

Completed · Not applicable

Conditions studied: HIV Infections

In brief

YouTHrive (YT) is a two-arm randomized control trial (RCT) to test the efficacy of an adapted version of the Thrive With Me (TWM) intervention for youth living with HIV (YLWH). In the RCT, intervention participants will have access to the full YouTHrive (YT) website- a mobile-enhanced private social networking website aimed at improving medication adherence for YLWH. The investigators will enroll up to 60 YLWH for formative work on YT, and 300 YLWH (15-24 years old) of all genders living in eight cities and randomize them to either the intervention condition or control condition. Assessments will be collected at baseline and 5-month follow-up.

Key facts

Study ID

NCT03149757

Run by

University of Minnesota

People needed

208

Starts

2017-05-16

Expected to finish

2022-05-31

Last updated by the study team

2023-07-03

Who can join

Age: 15 and older, up to 24. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 15-24 years of age at the enrollment visit;
• HIV-positive status;
• Residing in Chicago, Houston, NYC, Philadelphia, Atlanta, Tampa, or Raleigh/Durham/Chapel Hill areas and available to meet in-person or virtually with SRV staff for visits at baseline and 5-month follow-up assessment;
• English-speaking (since the intervention will be in English);
• Anticipated continuous internet access and SMS messaging for the intervention period (approximately 5 months);
• Not enrolled in another ART adherence intervention research study at the time of screening;
• Has or is willing to create an e-mail address to use during the study period;
• Did not attend an iTech Youth Advisory Board (YAB) or Youth Advisory Council (YAC) meeting where the YouTHrive study was presented or YouTHrive study materials were discussed.

You may not qualify if…

• Is younger than 15 years old or older than 24 years old at the enrollment visit;
• does not have an HIV-positive status;
• Does not reside in Chicago, Houston, NYC, Philadelphia, Atlanta, Tampa, or Raleigh/Durham/Chapel Hill areas and not available to meet with SRV staff for visits at baseline, and 5-month follow-up assessment;
• Does not speak English;
• Does not anticipate having continuous internet access and SMS messaging for the intervention period (approximately 5 months);
• Is enrolled in another ART adherence intervention research study at the time of screening;
• Does not have or is not willing to create an e-mail address to use during the study period;
• Is a member of an iTech Youth Advisory Board (YAB) or Youth Advisory Council (YAC).
• Participants who are or become pregnant during the study period will not be excluded.

Where it is running

• University of South Florida — Tampa, Florida, United States
• Emory University — Atlanta, Georgia, United States
• Cook County Hospital and Health Systems CORE Center — Chicago, Illinois, United States
• Montefiore Children's Hospital — The Bronx, New York, United States
• University of North Carolina at Chapel Hill — Chapel Hill, North Carolina, United States
• Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States
• Texas Children's Hospital — Houston, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.