Evaluating MMPs in Burns

Stopped early

Conditions studied: Burns, Thermal Burn, Thermal Injury

In brief

The objective of this study is to determine whether our chemical assay can be used to reliably predict graft take or failure in patients undergoing autologous skin grafting for treatment of acute burn injury.

Key facts

Study ID

NCT03148977

Run by

University of Florida

People needed

8

Starts

2017-06-09

Expected to finish

2020-12-08

Last updated by the study team

2021-03-26

Who can join

Age: 18 and older, up to 98. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18 years of age or older
• Admitted with acute burns injuries (flame, contact or scald) requiring at least one surgical excision and grafting operation will be considered for inclusion
• Burn injury less than one week old

You may not qualify if…

• Electrical, chemical or cold-induced burn injury
• Total body surface area burn >50 %
• Pre injury diagnosis of chronic renal insufficiency, liver failure, refusal to accept blood transfusion or withdrawal of care within three days of admission will also be exclusion criteria
• Patients not expected to survive
• Patients presenting with re-injury to previously burned and treated areas.
• Patients who present after receiving burn excision surgery out an outside facility for the current acute injury

Where it is running

• UF Health Cancer Hospital — Gainesville, Florida, United States
• UF Health Shands at the University of Florida — Gainesville, Florida, United States

Full record on ClinicalTrials.gov

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