Palbociclib After CDK and Endocrine Therapy (PACE)

Running, not enrolling · Phase 2

Conditions studied: Metastatic Breast Cancer

In brief

This research study is studying three combinations of drugs as treatments for breast cancer. The drugs involved in this study are: -Fulvestrant -Fulvestrant with Palbociclib -Fulvestrant with Palbociclib and Avelumab

Key facts

Study ID

NCT03147287

Run by

Dana-Farber Cancer Institute

People needed

220

Starts

2017-09-05

Expected to finish

2026-06-30

Last updated by the study team

2025-09-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• University of Miami — Miami, Florida, United States
• Emory University - Winship Cancer Institute — Atlanta, Georgia, United States
• Northwestern University — Chicago, Illinois, United States
• Indiana University — Indianapolis, Indiana, United States
• The University of Kansas Cancer Center - North — Kansas City, Kansas, United States
• The University of Kansas Cancer Center - Overland Park — Overland Park, Kansas, United States
• The University of Kansas Cancer Center — Westwood, Kansas, United States
• University of Louisville — Louisville, Kentucky, United States
• Eastern Maine Medical Center — Bangor, Maine, United States
• Boston Medical Center — Boston, Massachusetts, United States
• Dana-Farber Cancer Institute — Boston, Massachusetts, United States
• Dana-Farber at St. Elizabeth's Medical Center — Brighton, Massachusetts, United States
• DF/BWCC at Milford Regional Medical Center — Milford, Massachusetts, United States
• DF/BWCC in clinical affiliation with South Shore Hospital — South Weymouth, Massachusetts, United States
• The University of Kansas Cancer Center - Lee's Summit — Lee's Summit, Missouri, United States
• Washington University — St Louis, Missouri, United States
• Dana-Farber/New Hampshire Oncology-Hematology — Londonderry, New Hampshire, United States
• University of North Carolina at Chapel Hill — Chapel Hill, North Carolina, United States
• University of Pennsylvania — Philadelphia, Pennsylvania, United States
• Vanderbilt University Medical Center — Nashville, Tennessee, United States
• Baylor University — Houston, Texas, United States
• Aurora Cancer Care — Milwaukee, Wisconsin, United States

Full record on ClinicalTrials.gov

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