Sick-Day Protocol to Improve Outcomes in Chronic Kidney Disease

Completed · Not applicable

Conditions studied: Safety Issues, Chronic Kidney Diseases

In brief

The benefits of renin angiotensin system (RAS) blockers and diuretics for blood pressure control are well-established in chronic kidney diseases (CKD) patients; however, these agents may become hazardous on "sick-days" that lead to volume depletion (dehydration), and increase the risk of kidney function loss and acute kidney injury (AKI). It is not known how frequent significant sick-days occur in CKD patients, or whether a patient self-managed Sick-Day Protocol (SDP) that temporarily holds RAS blocker, diuretics, or other high risk medication in an effort to preserve renal function, or prevent AKI. The purpose of the study is to asses if a SDP, monitored remotely with a weekly automated phone survey , can improve outcomes in CKD (such as slow renal function loss and AKI episodes) and reduce preventable service utilization versus usual care.

Key facts

Study ID

NCT03141905

Run by

University of Maryland, Baltimore

People needed

342

Starts

2017-10-16

Expected to finish

2020-10-07

Last updated by the study team

2021-04-14

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Veterans with prescription for any type of RAS blocker, diuretic, Metformin or NSAID

You may not qualify if…

• Expected death or dialysis within 6 months
• No home or cellular telephone

Where it is running

• Baltimore VA Medical Center — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.