Comparison of Oxygenation and Ventilation With a Novel Nasal Mask Versus Standard of Care During Colonoscopy

Completed · Not applicable

Conditions studied: Colonoscopy, Oxygenation, Ventilation

In brief

Nasal continuous positive airway pressure (nCPAP) has been shown to effectively relieve upper airway obstruction in patients with OSA as it creates a pneumatic stent in the hypopharynx that reduces obstruction and allows for continuous oxygenation. Nasal ventilation was also proven to be more effective than combined oral-nasal ventilation during induction of general anesthesia in adult subjects. However, it is not clear if nasal mask can be used safely for oxygenation and ventilation in patients undergoing colonoscopy. The SuperNO2VA™ device is a new commercially available nasal mask that provides both nasal CPAP and nasal mask ventilation. The objective of this study is to compare the efficacy of oxygenation and ventilation during colonoscopy using the novel nasal mask, SuperNO2VA™, and standard care with nasal cannula.

Key facts

Study ID: NCT03139448
Run by: Vanderbilt University Medical Center
People needed: 174
Starts: 2017-05-17
Expected to finish: 2017-10-06
Last updated by the study team: 2019-02-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Patients 18 years or older
BMI of 30-50
ASA 1-3 Scheduled for colonoscopy with sedation

You may not qualify if…

Untreated ischemic heart disease
Acute and chronic respiratory disorders, including COPD and asthma
Emergent procedures
Planned use of an invasive airway (ie: supra-glottic device, LMA, etc)
Pregnant women
Nasal or oral disease resulting in difficulty of either nasal breathing or mouth breathing
Patient refusal

Where it is running

Vanderbilt University Medical Center — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.