Opioid Analgesia for MAB

Completed · Phase 4 · Has a placebo group

Conditions studied: MAB, Pain

In brief

Our primary objective will be to determine if a strong opioid, oxycodone, given at a dose recommended for severe pain in addition to ibuprofen decreases maximum pain scores compared to ibuprofen and placebo in women undergoing medical abortion (MAB). Results of this study will help future providers understand whether prescribing opioids are an important adjunct for pain control in women undergoing MAB.

Key facts

Study ID

NCT03139240

Run by

Oregon Health and Science University

People needed

172

Starts

2017-05-01

Expected to finish

2018-05-31

Last updated by the study team

2019-08-28

Who can join

Age: 18 and older, up to 50. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Aged 18 years or older
• Seeking elective medical abortion
• In good health
• Pregnancy with intrauterine gestational sac up to 10 0/7 weeks, dated by ultrasound
• Able and willing to receive text messages via phone
• Literate in English
• Able and willing to give informed consent and agree to the study terms
• Have assistance at home; no motor vehicle use while taking study medications

You may not qualify if…

• Lack of access to cell phone and texting capabilities
• Early pregnancy failure
• Contraindications to the study medications: Oxycodone, Ibuprofen
• Contraindications to medical abortion with Mifepristone or Misoprostol
• History of methadone or heroin use
• Used alcohol in the past 24 hours
• Used marijuana >4 times per week
• Any opioid in the past 30 days
• Using additional pain medications

Where it is running

• Site 1 — Beaverton, Oregon, United States

Full record on ClinicalTrials.gov

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