Nocturnal Hypertension and Non-Dipping Blood Pressure

Completed · Not applicable

Conditions studied: Hypertension, Obstructive Sleep Apnea

In brief

The purpose of this study is to determine if high salt diet contributes to high nighttime blood pressure. The investigators will determine if high compared to low salt diet increases 24-hour blood pressure levels. The investigators will also determine if high salt diet affects blood vessel stiffness, cardiac output, and sleep apnea. The study will also determine how high salt diet affects the activity of certain genes related to control of blood pressure. A total of 60 participants will be enrolled in the study.

Key facts

Study ID

NCT03128177

Run by

University of Alabama at Birmingham

People needed

59

Starts

2016-01-01

Expected to finish

2020-03-31

Last updated by the study team

2020-06-11

Who can join

Age: 48 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Nocturnal hypertension

You may not qualify if…

• Stage 2 clinic hypertension
• History of congestive heart failure
• Chronic kidney disease,
• Diabetes with insulin use
• History of a cardiovascular event
• Pregnant or nursing
• Current use of continuous positive airway pressure
• Shift work
• A known circadian rhythm disorder

Where it is running

• David A. Calhoun, MD — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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