Regulation of Inflammatory Genes in Psoriasis

Recruiting now

Conditions studied: Psoriasis, Inflammation

In brief

Psoriasis is a chronic and recurrent skin disorder characterized by marked inflammatory changes in the skin. An extensive cytokine network including generated by activated dendritic cells and T cells mediates the formation of psoriatic lesions. These immune-response parameters can be used as markers in the severity and management of the disease after further in-depth studies.

Key facts

Study ID

NCT03125655

Run by

University of Alabama at Birmingham

People needed

13

Starts

2014-04-22

Expected to finish

2028-04-28

Last updated by the study team

2026-04-06

Who can join

Age: 19 and older, up to 99. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Clinical diagnosis of psoriasis
• Must be age 19 or older.
• Must be Fitzpatrick skin type I, II, III, IV, V, VI.

You may not qualify if…

• Subjects who do not have photosensitive disease and are not on photosensitizing medications.
• Subjects with a history of keloids (who are more likely to develop hypertrophic scars following skin biopsy).
• Subjects who have an allergy to local anesthetics, antibiotics and/or anticoagulants.
• Subjects who are pregnant.

Where it is running

• The Kirklin Clinic — Birmingham, Alabama, United States (enrolling)

Full record on ClinicalTrials.gov

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