An Algorithmic Approach to Ventilator Withdrawal at the End of Life

Completed · Not applicable

Conditions studied: Critical Care, Palliative Care

In brief

The proposed study is an important, under-investigated area of ICU care for terminally ill patients undergoing terminal ventilator withdrawal. The proposed research has relevance to public health because an algorithmic approach to the ventilator withdrawal process will enhance clinicians' ability to conduct the process while assuring patient comfort, using opioids and/or benzodiazepines effectively.

Key facts

Study ID

NCT03121391

Run by

Wayne State University

People needed

165

Starts

2017-04-20

Expected to finish

2022-07-31

Last updated by the study team

2022-11-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients undergoing ventilator withdrawal

You may not qualify if…

• Patients who are conscious and cognitively intact
• Patients who will undergo organ donation after ventilator withdrawal
• Patients who are brain dead
• Patients with bulbar amyotrophic lateral sclerosis
• Patients with C-1 to C-4 quadriplegia
• Patients with locked-in syndrome

Where it is running

• Detroit Receiving Hospital — Detroit, Michigan, United States
• Harper University Hospital — Detroit, Michigan, United States
• Henry Ford Health System — Detroit, Michigan, United States
• William Beaumont Hospital — Royal Oak, Michigan, United States
• Ascension Providence Hospital — Southfield, Michigan, United States

Full record on ClinicalTrials.gov

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