ACCESS to the Cardiac Cath Lab in Patients Without STEMI Resuscitated From Out-of-hospital VT/VF Cardiac Arrest

Stopped early · Not applicable

Conditions studied: Cardiac Arrest Due to Underlying Cardiac Condition, Ventricular Fibrillation, Cardiopulmonary Arrest With Successful Resuscitation

In brief

To determine if survival to hospital discharge with good neurological outcome for adults ages 18-75 who are resuscitated from out-of-hospital VT/VF cardiac arrest without clinical signs of a heart attack do better by going straight to the cardiac catheterization laboratory or admitted to the intensive care unit for evaluation. The investigators think a large portion of resuscitated patients presenting with VT/VF have ischemic heart disease which is the cause for the arrest. And prompt access to the cardiac catheterization laboratory to reverse the blocked artery will improve survival with good neurological outcomes.

Key facts

Study ID

NCT03119571

Run by

University of Minnesota

People needed

65

Starts

2017-12-12

Expected to finish

2019-11-26

Last updated by the study team

2021-01-27

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult presumed or known to be 18-75 years old
• Resuscitated from OOHCA
• Initial cardiac arrest rhythm of pulseless VT/VF (including patients treated with an AED)
• No ST-segment elevation MI (No STEMI) (or STEMI-equivalent syndrome) on ED 12-lead ECG (as interpreted by a physician)

You may not qualify if…

• Initial non-shockable out-of-hospital cardiac arrest rhythm (pulseless electrical activity or asystole)
• Valid do not resuscitate orders (DNR),
• Blunt, penetrating, or burn-related injury, drowning, electrocution or known overdose,
• Known prisoners
• Known pregnancy,
• ST-segment elevation on ED 12-lead ECG (as interpreted by a physician)
• Absolute contraindications to emergent coronary angiography including,
• known anaphylactic reaction to angiographic contrast media,
• active gastrointestinal or internal bleeding, or
• severe concomitant illness that drastically shortens life expectancy or increases risk of the procedure.
• Suspected or confirmed intracranial bleeding
• Refractory cardiac arrest (prior to randomization)
• Patients meeting ACCESS Trial eligibility criteria initially seen in an outside hospital and then transferred to an ACCESS Trial participating hospital

Where it is running

• Grady Memorial Hospital — Atlanta, Georgia, United States
• Indiana University Health Methodist Hospital — Indianapolis, Indiana, United States
• University Hospital — Ann Arbor, Michigan, United States
• St. Joseph Mercy Hospital — Ypsilanti, Michigan, United States
• North Memorial Medical Center — Brooklyn Center, Minnesota, United States
• Fairview Southdale Hospital — Edina, Minnesota, United States
• Hennepin County Medical Center — Minneapolis, Minnesota, United States
• University of Minnesota Medical Center, Fairview — Minneapolis, Minnesota, United States
• Methodist Hospital — Saint Louis Park, Minnesota, United States
• Regions Hospital — Saint Paul, Minnesota, United States
• St. Joseph's Hospital — Saint Paul, Minnesota, United States
• University of Cincinnati — Cincinnati, Ohio, United States
• Allegheny General Hospital — Pittsburgh, Pennsylvania, United States
• University of Pittsburgh — Pittsburgh, Pennsylvania, United States
• Miriam Hospital — Providence, Rhode Island, United States
• Rhode Island Hospital — Providence, Rhode Island, United States
• Parkland Memorial Hospital — Dallas, Texas, United States
• University of Utah — Salt Lake City, Utah, United States
• Virginia Commonwealth University Hospital — Richmond, Virginia, United States
• Harborview Medical Center — Seattle, Washington, United States
• Medical College of Wisconsin Froedtert Hospital — Milwaukee, Wisconsin, United States
• St. Paul's Hospital — Vancouver, British Columbia, Canada
• Vancouver General Hospital — Vancouver, British Columbia, Canada

Full record on ClinicalTrials.gov

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