Foley Catheter Related Bladder Discomfort (FCRBD): Role of Neutrophil Cells
Stopped early
Conditions studied: Urethra Injury, Catheter Site Discomfort
In brief
Urinary \[Foley\] catheters \[tubes\] are commonly placed in patients undergoing surgery; approximately 25% of surgical patients will receive one. Among patients who receive urinary catheters, discomfort associated with the Foley catheter is common; between 47-90% of patients experience catheter related bladder discomfort \[CRBD\]. Presence of a foreign object in the bladder even for short periods of time may result in symptoms such as a burning sensation, pain in the lower abdomen, muscle spasms and a sense of urgency to urinate. There is some evidence that suggests that hospital-acquired urinary tract infections are directly related to catheter placement, which causes mechanical damage and local inflammation to the urethra and the bladder. Based on research conducted on a similar mechanism where an airway tube is inserted into a patients throat for delivery of general anesthesia - we hypothesize that CRBD is related to injury and inflammation caused by the catheter placement and that this occurs in a sterile environment.
Key facts
- Study ID
- NCT03118284
- Run by
- Washington University School of Medicine
- People needed
- 58
- Starts
- 2016-11-21
- Expected to finish
- 2017-08-28
- Last updated by the study team
- 2018-11-15
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Ages 18 to 75.
- American Society of Anesthesiologists Physical Status Classification (ASA) I, II, and III, per CPAP assessment.
- Planned Foley catheter placement with surgery and hospitalization.
- Scheduled elective surgery (i.e., orthopedic, neurosurgical, spine surgery, cardiac, thoracic surgery, ear nose and throat surgery).
- Anticipated length of Foley catheter requirement up to 72 hours.
- Ability to provide informed consent.
You may not qualify if…
- Visible blood in the urine as evident upon sample collection.
- More than one attempt to place the Foley catheter as documented by RN in OR.
- Planned surgical procedure involving the urinary system
- On dialysis and/or anuric
- Urinary tract infection (UTI) as documented by primary team within 24 hours of surgery
- Pregnancy or lactating.
Where it is running
- Washington University in St Louis — St Louis, Missouri, United States
Full record on ClinicalTrials.gov
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