Project PROTECT: Protecting Nursing Homes From Infections and Hospitalization

Completed · Phase 4

Conditions studied: Hospitalization, Infection

In brief

This is a cluster-randomized trial of nursing homes to assess whether decolonization with routine chlorhexidine bathing and periodic use of nasal antiseptics can reduce hospitalizations associated with infections, antibiotic utilization, and multi-drug resistant organism (MDRO) prevalence. The comparator arm will be routine bathing care.

Key facts

Study ID

NCT03118232

Run by

University of California, Irvine

People needed

13952

Starts

2017-04-03

Expected to finish

2023-10-10

Last updated by the study team

2023-12-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Nursing homes will be eligible to participate if they meet the following criteria:
• Licensed nursing home in Orange County or Southern Los Angeles County serving adults
• Minimal use of chlorhexidine bathing*
• Minimal use of nasal decolonization* *Minimal use defined as <15% of residents receiving at least one chlorhexidine bath or nasal decolonization treatment during their nursing home stay.

You may not qualify if…

• Nursing homes will not be eligible to participate if they meet the following criteria:
• Facilities routinely using decolonization
• Dedicated psychiatric nursing homes
• Facilities with a resident population with >=20% combative patients
• Pediatric facilities
• Note: in any participating nursing home, residents with active end-of-life comfort care only measures are excluded

Where it is running

• Buena Vista Care Center — Anaheim, California, United States
• Walnut Village Rehabilitation and Care Center — Anaheim, California, United States
• Anaheim Crest Nursing Center — Anaheim, California, United States
• Sun Mar Nursing Center — Anaheim, California, United States
• West Anaheim Extended Care — Anaheim, California, United States
• Bel Tooren Villa Convalescent Hospital — Bellflower, California, United States
• Capistrano Beach Care Center — Capistrano Beach, California, United States
• Downey Care Center — Downey, California, United States
• Gordon Lane Care Center — Fullerton, California, United States
• Windsor Gardens Care Center of Fullerton — Fullerton, California, United States
• Terrace View Care Center — Fullerton, California, United States
• Pacific Haven Subacute Healthcare Center — Garden Grove, California, United States
• Las Flores Convalescent Hospital — Gardena, California, United States
• Park Regency Care Center — La Habra, California, United States
• Regency Oaks Post Acute Care Center — Long Beach, California, United States
• Windsor Convalescent of North Long Beach — Long Beach, California, United States
• Bixby Knolls Healthcare Center — Long Beach, California, United States
• Pacific Villa Inc. — Long Beach, California, United States
• Vista Cove Care Center at Long Beach — Long Beach, California, United States
• Intercommunity Care Center — Long Beach, California, United States
• Royal Oaks Care Center — Lynwood, California, United States
• Norwalk Skilled Nursing and Wellness Center — Norwalk, California, United States
• Villa Elena Care Center — Norwalk, California, United States
• Harbor Post-Acute Care Center — Torrance, California, United States
• Heritage Rehabilitation Center — Torrance, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.