The K-Map Study, Global Prevalence of KC

Recruiting now

Conditions studied: Keratoconus

In brief

Keratoconus is a ocular disease classified under ectatic diseases which often results in bilateral and asymmetrical corneal distortion. It usually affects patients at young age and can cause severe visual loss. The overall goal of this study is to assess the prevalence of keratoconus (KC) in children and adolescents in various regions of the world based on modern tomographic imaging methods, and to verify whether the occurrence rates reported from literature should be corrected. Our hypothesis is that the prevalence of the disease is much higher than that traditionally reported. At each site, corneal tomography examinations (Pentacam) will be performed bilaterally in children and adolescents, who are not ill or with any ophthalmological symptom. The population to be studied will be composed of children and adolescents on medical visits for non-ophthalmologic reasons, aged between 6 and 20 years. Multiple cities, from different continents (North America, South America, Asia and Europe) will participate.

Key facts

Study ID

NCT03115710

Run by

University Hospital, Geneva

People needed

20000

Starts

2015-12-28

Expected to finish

2030-02-01

Last updated by the study team

2025-08-11

Who can join

Age: 6 and older, up to 23. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male or female, 6-23 years of age.
• Subjects seen for a non-ophthalmic appointment
• Provide signed and dated patient consent form (signed by parents / legal guardians).
• Willing to comply with all study procedures and be available for the duration of the study

You may not qualify if…

• Patients with a preexisting ocular disease / condition
• Pregnancy or breastfeeding

Where it is running

• Study site — Bukhara, Uzbekistan (enrolling)
• Eye Hospital of Wenzhou Medical College — Wenzhou, China (enrolling)
• Study site — Zagreb, Croatia (enrolling)
• Study site — Alexandria, Egypt (enrolling)
• Study site — Homburg, Germany (enrolling)
• Study site — Isfahan, Iran (enrolling)
• Study site — Amman, Jordan (enrolling)
• Study site — Monterrey, Mexico (enrolling)
• Study site — Lima, Peru (enrolling)
• USC Roski Eye Institute — Los Angeles, California, United States (enrolling)
• King Saud University — Riyadh, Saudi Arabia
• Ufa Eye Research Intitute — Ufa, Russia

Full record on ClinicalTrials.gov

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