The Effects of Energy Imbalance on Food Intake Behaviors

Completed · Not applicable

Conditions studied: Obesity

In brief

This study will determine whether changes in energy balance alter regional neuronal activation of brain regions associated with food intake in individuals screened to be either resistant or prone to obesity. Specifically, it will determine whether foods of "hedonic" value elicit changes in regional neuronal activity in the fasted and fed state in "obese-resistant" and "obese-prone" men and women in varying states of energy balance.

Key facts

Study ID

NCT03112161

Run by

University of Colorado, Denver

People needed

76

Starts

2005-06-14

Expected to finish

2015-10-01

Last updated by the study team

2017-04-13

Who can join

Age: 25 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• In the obese-prone group:
• BMI between 20-30
• Report at least one obese first-degree relative
• Self-describe as "struggling" with weight
• Weight-stable for at least 3 months prior to study participation
• In the obese-resistant group:
• BMI between 17-25
• Report no obese first-degree relatives
• Self-describe as "naturally thin" and have never been overweight
• Overall weight stability

You may not qualify if…

• Significant medical or psychiatric disease
• History of eating disorder
• Left handed
• Unable to complete an MRI scan (e.g., metal in body, claustrophobic)

Where it is running

• University of Colorado Anschutz Medical Campus — Aurora, Colorado, United States

Full record on ClinicalTrials.gov

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