Exercise Program During Chemotherapy in Metastatic Colorectal Cancer

Stopped early · Not applicable

Conditions studied: Stage IV Colorectal Cancer

In brief

This pilot clinical trial studies how well aerobic exercise works in improving quality of life and health-related outcomes in patients with stage IV colorectal cancer undergoing chemotherapy. Aerobic exercise during chemotherapy may improve quality of life and reduce fatigue and inflammation in the blood related to heart disease and diabetes in patients with stage IV colorectal cancer.

Key facts

Study ID

NCT03111823

Run by

University of Southern California

People needed

2

Starts

2016-07-07

Expected to finish

2018-07-05

Last updated by the study team

2018-08-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Newly diagnosed metastatic (stage IV) colorectal cancer
• Undergoing chemotherapy (have had 1 or 2 chemotherapy cycles infused at time of data collection; this will allow for any systemic inflammatory changes due to chemotherapy to set in); only patients with 1st or 2nd line therapy will be included
• Able to initiate a supervised exercise program (free from any CV, respiratory or musculoskeletal disease or joint problems that preclude moderate physical activity)
• Free from uncontrolled chronic disease including diabetes, hypertension, or thyroid disease
• Currently participate in less than 60 minutes of physical activity/week
• Willing to travel to the exercise facility at University of Southern California (USC) (parking fees and public transportation permits will be provided)
• Speak English or Spanish

You may not qualify if…

• Uncontrolled hypertension or other uncontrolled chronic disease (e.g. diabetes mellitus, thyroid disease, pulmonary disease, etc)
• Moderate to highly active level of physical activity (e.g. currently participating in > 60 minutes of moderate aerobic activity weekly)
• Orthopedic or other restrictions or contraindications to exercise
• Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
• Patients must not be pregnant or nursing due to the potential for congenital abnormalities and the potential of this regimen to harm nursing infants

Where it is running

• Los Angeles County-USC Medical Center — Los Angeles, California, United States
• USC / Norris Comprehensive Cancer Center — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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