Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery

Completed · Phase 2

Conditions studied: Carpal Tunnel Syndrome, Dupuytren Contracture, Trigger Digit, Ganglion Cysts, De Quervain Disease

In brief

This study is about pain control and medication following outpatient soft-tissue hand surgery. We hope to learn if ibuprofen and acetaminophen will achieve similar pain relief and satisfaction when compared with oxycodone alone.

Key facts

Study ID: NCT03111186
Run by: University of Southern California
People needed: 40
Starts: 2017-04-24
Expected to finish: 2019-05-01
Last updated by the study team: 2019-09-26

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

age greater than 18 years
scheduled to undergo elective outpatient soft tissue hand surgery for one of the following procedures: Carpal tunnel release, Dupuytren contracture release, trigger digit release, ganglion cyst removal, de Quervain's release.
primary language is English or Spanish

You may not qualify if…

any pre-existing condition requiring preoperative opiate analgesia, eg chronic pain syndrome
allergy to acetaminophen, ibuprofen, or oxycodone
renal impairment or liver disease either documented based on history or when preoperative creatinine, BUN, or liver function tests are outside the normal range provided by the lab
peptic ulcer disease or any history of gastrointestinal bleeding
coagulopathy documented on history, review of systems, or based on preoperative lab testing where PT, PTT, or INR are outside the normal range provided by the lab
pregnancy based on positive beta-HCG test which is performed on the day of the surgical procedure as is standard protocol

Where it is running

Keck School of Medicine of the University of Southern California — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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