Using Breath Metabolites to Determine Specific Virus Infection in Asthmatic Patients

Completed

Conditions studied: Upper Respiratory Tract Infections, Asthma, Exhaled Breath

In brief

Respiratory virus infections cause a majority of asthma exacerbations in the fall to spring months. Current diagnostic platforms for respiratory viruses have limitations including cost, availability, and invasiveness. The use of noninvasive breath collection to analyze breath metabolites may be used to differentiate virus-infected asthmatics from other causes of acute asthma exacerbations.

Key facts

Study ID

NCT03089970

Run by

University of California, Davis

People needed

19

Starts

2017-02-01

Expected to finish

2020-09-01

Last updated by the study team

2021-08-20

Who can join

Age: 12 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Asthma, Age ≥12, Symptoms/signs of an early asthma exacerbation, Ability to provide exhaled breath condensate (EBC) x15 min, Body mass index (BMI) ≥18

You may not qualify if…

• Chronic lung diseases other than asthma (e.g., chronic obstructive pulmonary disease [COPD], lung cancer, fibrotic lung disease, etc.), Smoking in the past 7 days, Eating or non-clear liquids <4 hrs prior to EBC collection, Pregnancy

Where it is running

• University of California Davis Medical Ceneter — Sacramento, California, United States

Full record on ClinicalTrials.gov

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