Postural Changes During Right Heart Catheterization

Stopped early

Conditions studied: Pulmonary Hypertension, Right Heart Failure Due to Pulmonary Hypertension

In brief

Hemodynamic measurements obtained during pulmonary artery catheterization are essential for the diagnosis and classification of pulmonary hypertension. Traditionally, right heart catheterization (RHC) is done in the supine position. Cardiac output is known to change significantly based on position, due to the effects of gravity on venous return. There has not been a systematic investigation into these postural effects on pulmonary arterial pressures nor their effect on the diagnosis of pulmonary hypertension. It is our intent to study the differences in measurements obtained during RHC when the patient is supine, seated, and standing.

Key facts

Study ID

NCT03089164

Run by

University of North Carolina, Chapel Hill

People needed

2

Starts

2017-05-01

Expected to finish

2018-01-29

Last updated by the study team

2019-06-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• All patients that are 18 years or older regardless of gender or race,
• are referred for RHC for evaluation of possible Pulmonary Arterial Hypertension (PAH)
• provide informed consent

You may not qualify if…

• Inability to obtain pulmonary artery pressure or PCWP

Where it is running

• University of North Carolina, Chapel Hill — Chapel Hill, North Carolina, United States

Full record on ClinicalTrials.gov

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