Cognitive, Behavioral, and Functional Change in Behavioral Variant Frontotemporal Dementia (bvFTD)

Completed

Conditions studied: Frontotemporal Dementia, Behavioral Variant Frontotemporal Dementia

In brief

The objectives of the study are to; (1) estimate the change in disease -related cognitive decline over 1 year on a battery of cognitive tests administered to participants with early-stage symptomatic Behavioral Variant Frontotemporal Dementia (bvFTD) phenotypic variant; (2) identify the cognitive test or brief battery of cognitive tests which are the most sensitive to detect bvFTD progression; (3) determine the optimal schedule of administration of cognitive tests to detect bvFTD progression; (4) evaluate the relationship between cognitive tests and measures of behavior, function, caregiver's burden, quality of life (QOL); and (5) obtain blood samples for genetic and exploratory biomarkers correlations.

Key facts

Study ID

NCT03088956

Run by

Biogen

People needed

47

Starts

2018-01-19

Expected to finish

2019-09-23

Last updated by the study team

2020-06-16

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.

Where it is running

• Research Site — Birmingham, Alabama, United States
• Research Site — Los Angeles, California, United States
• Research Site — Boca Raton, Florida, United States
• Research Site — Boca Raton, Florida, United States
• Research Site — Atlanta, Georgia, United States
• Research Site — Elk Grove Village, Illinois, United States
• Research Site — Baltimore, Maryland, United States
• Research Site — Rochester, Minnesota, United States
• Research Site — Columbus, Ohio, United States
• Research Site — Philadelphia, Pennsylvania, United States
• Research Site — Knoxville, Tennessee, United States
• Research Site — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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