The Effects of Water Temperature on the Cold Pressor Test
Completed
Conditions studied: Chronic Pain
In brief
This current study is intended to be completed under the umbrella of the current GHUCCTS IRB- approved study "Opioid-Induced Hyperalgesia In Prescription Opioid Abusers: Effects of Pregabalin" (Lyrica study) (PRO00000669). In this proposed study, 10 healthy male, 10 healthy female participants and 5 male, 5 female OIH participants (from the parent Lyrica study), who are prescription opioid abusers with chronic pain currently taking Suboxone, will be asked to take the cold pressor test at 1, 5, and 9 degrees Celsius and to report the time at which pain has completely gone away following each test. The purpose of this study is to examine how the water temperature of the cold pressure test might affect the participants' response (i.e., the participants pain threshold and pain tolerance) and to see if there is a difference in how each participation group is affected.
Key facts
- Study ID
- NCT03083626
- Run by
- Georgetown University
- People needed
- 20
- Starts
- 2015-05-01
- Expected to finish
- 2017-03-31
- Last updated by the study team
- 2017-04-20
Who can join
Age: 21 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Between 21 and 65 years old
- On suboxone or methadone for at least ten days
- Currently experiencing chronic low back or arthritis pain
You may not qualify if…
- Be on any opioid analgesic
- Have a neurological or psychiatric illness (i.e., schizophrenia, Raynaud's disease, urticaria, stroke) that would affect pain responses
- Have an abnormal screening EKG, history of heart disease, stroke, liver or kidney disease or acute hepatitis, or currently have a pacemaker or uncontrolled high blood pressure.
Where it is running
- Georgetown University Medical Center — Washington D.C., District of Columbia, United States
Full record on ClinicalTrials.gov
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