Cross-Cultural Use of Performance-Based Functional Assessment in Alzheimer's Disease

Completed

Conditions studied: Mild Cognitive Impairment, Healthy Controls

In brief

This study plans to assess the effectiveness of performance-based functional assessments (PBFAs) and cognitive assessments in diagnosing Alzheimer's disease in Hispanic/Latino populations. The information from this study will be analyzed with data from the Rocky Mountain Alzheimer's Disease Center Bio-AD study (NCT02612376).

Key facts

Study ID

NCT03081546

Run by

University of Colorado, Denver

People needed

41

Starts

2017-05-04

Expected to finish

2018-09-01

Last updated by the study team

2021-08-09

Who can join

Age: 55 and older, up to 85. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Persons with age-related MCI or AD according to clinical diagnosis, consistent with National Institute on Aging-Alzheimer's Association (NIA-AA) diagnostic criteria
• Community-dwelling controls
• Age > 55 years
• Have been enrolled and completed at least one visit in the Bio-AD study and consent to access their data (the Rocky Mountain Alzheimer's Disease Center Bio-AD study (clinicaltrials.gov identifier: NCT02612376))
• Have capacity to provide consent; capacity will be assessed at the time of consent
• Ability to complete baseline assessments
• Has informant (study partner) available to complete functional interviews/survey measures

You may not qualify if…

• Presence of concomitant medical, neurological, or psychiatric illness or condition that in the opinion of the investigators would confound interpretation of study results. These include:
• Korsakoff encephalopathy;
• active substance abuse;
• hepatitis C;
• opportunistic brain infection;
• brain tumor;
• active neoplastic disease (skin tumors other than melanoma are not exclusionary; participants with stable prostate cancer may be included at the discretion of the project director);
• multiple sclerosis;
• history of clinically significant stroke;
• current evidence or history in the past 2 years of
• focal brain lesion,
• head injury with loss of consciousness in the past year, or
• DSM-5 criteria for any major psychiatric disorder, including
• psychosis,
• uncontrolled major depression,
• bipolar disorder,
• alcohol or substance abuse;
• blindness,
• deafness or
• any other disability which may prevent the participant from participating or cooperating in the protocol.
• Prisoners
• Any contraindication for MRI

Where it is running

• University of Colorado Anschutz Medical Campus — Aurora, Colorado, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.