Open Label Study to Assess the Effect of Secukinumab in Moderate to Severe Papulopustular Rosacea

Completed · Phase 1/Phase 2

Conditions studied: Papulopustular Rosacea

In brief

This is a study to determine whether secukinumab is a potential therapy for those with papulopustular rosacea. We will observe whether this drug decreases the size and/or amount and severity of the pustules of those who suffer from rosacea.

Key facts

Study ID

NCT03079531

Run by

Anne Chang

People needed

24

Starts

2017-06-21

Expected to finish

2019-01-25

Last updated by the study team

2020-02-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• moderate to severe papulopustular rosacea defined clinically using the grading system of Wilkin et al. (2004) as having at least ten lesions (either papules or pustules) on face at time of enrollment
• age 18 years or greater willing and able to understand and sign informed consent form

You may not qualify if…

• known hypersensitivity to secukinumab
• topical or oral anti-rosacea medication usage for 28 days prior to enrollment
• active Crohn's disease, as secukinumab may exacerbate this disease
• active infection including tuberculosis, hepatitis B or C, human immunodeficiency virus
• participants with latent tuberculosis will need to have treatment initiated prior to starting study drug
• pregnant or lactating
• active and/or uncontrolled medical conditions that may interfere with study procedures or obscure rosacea assessment such as cutaneous lupus
• use of retinoids within past 3 months of enrollment
• use of antibiotics within 4 weeks of enrollment
• use of light based or laser treatment to face within 8 weeks of enrollment
• use of topical or systemic steroids within 4 weeks of enrollment
• acne conglobate, acne fulminans, chloracne, severe acne requiring systemic treatment

Where it is running

• Stanford Dermatology — Redwood City, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.