Cardiac Resynchronization Therapy in Pulmonary Hypertension

Completed · Not applicable

Conditions studied: Pulmonary Hypertension

In brief

This study is being conducted to determine whether patients with advanced pulmonary hypertension when treated with cardiac resynchronization therapy improve hemodynamically and/or receive clinical benefit.

Key facts

Study ID

NCT03077139

Run by

Dr. Daniel P Morin, MD MPH FHRS

People needed

6

Starts

2012-11-29

Expected to finish

2017-03-23

Last updated by the study team

2017-09-20

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Pulmonary hypertension, defined as pulmonary artery systolic pressure greater than 40 mm Hg by transthoracic echocardiogram or right heart catheterization
• LVEF ≥ 50%
• Baseline 6MWT distant <400 meters
• Baseline NYHA Functional class ≥ III

You may not qualify if…

• LVEF < 50%
• 6MWT duration > 400 meters
• NYHA Functional class < III
• Left bundle branch block
• Non-sinus rhythm
• Severe aortic stenosis (Aortic valve area < 1 cm2)
• Severe mitral regurgitation
• Acute cardiac failure
• Dependency on intravenous inotropies
• Severe obstructive pulmonary disease
• Hypertrophic obstructive cardiomyopathy
• Amyloidosis
• Dependence on pacing

Where it is running

• Ochsner Medical Center — New Orleans, Louisiana, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.