Reward Processing in Mental Illness
Completed
Conditions studied: Early-onset Schizophrenia
In brief
The purpose of this study is to examine the nature of reward processing dysfunctions in schizophrenia using neuroimaging techniques that capture in vivo brain functioning, such as EEG and fMRI.
Key facts
- Study ID
- NCT03068793
- Run by
- Susanna Fryer
- People needed
- 80
- Starts
- 2013-10-01
- Expected to finish
- 2019-06-30
- Last updated by the study team
- 2019-07-15
Who can join
Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- The subject population will include 18 to 30 year old participants of any gender, race, and ethnicity. All subjects will be able to speak and understand English.
- Schizophrenia subjects:
- Patients must be diagnosed with DSM-IV schizophrenia, schizophreniform, or schizoaffective disorder based on a SCID-P interview.
- Depression subjects:
- Patients must be diagnosed with DSM-V Major Depressive Disorder based on a SCID-P interview.
- Post Traumatic Stress Disorder subjects:
- Patients must be diagnosed with DSM-V Post Traumatic Stress Disorder based on a SCID-P interview.
- Gambling Disorder subjects:
- Patients must be diagnosed with DSM-V Gambling Disorder based on a SCID-P interview.
- Comparison subjects:
- Control participants must not have past or present Axis I diagnosis as determined by the SCID-NP.
You may not qualify if…
- All subjects:
- A hearing deficit greater than 40dB in both ears detected during the hearing test
- Substance dependence, as per clinical judgment, in the past 1 year (except caffeine and nicotine)
- A history of significant medical/neurological disease such as cardiac, thyroid, renal, hepatic or neurological
- History of head injury with loss of consciousness greater than 15 minutes
- Any other condition or medication, which in the opinion of the investigator would preclude participation in the study.
- Non-English speaking.
- Comparison subjects:
- Any first-degree relative with schizophrenia or bipolar disorder.
Where it is running
- San Francisco VA Medical Center — San Francisco, California, United States
Full record on ClinicalTrials.gov
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