Organ Preservation in Locally Advanced Rectal Cancer

Recruiting now · Not applicable

Conditions studied: LOCALLY ADVANCED RECTAL CANCER

In brief

PRONAR trial aims to assess if treatment with organ preservation in stage II and III rectal cancer after a complete or almost complete response to neoadjuvant treatment is feasible and safe in our environment. The main objective of this project is to implement the organ preservation strategy in the treatment of rectal cancer in our environment within a clinical study that allows the analysis of its results in terms of survival. The secondary objective is to assess local relapse, distant relapse and quality of life.

Key facts

Study ID

NCT03064646

Run by

Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana

People needed

30

Starts

2017-03-10

Expected to finish

2027-02-01

Last updated by the study team

2018-09-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with confirmed histopathological diagnosis of rectal adenocarcinoma.
• Patients treated with neoadjuvant chemoradiotherapy or neoadjuvant radiotherapy associated or not with induction chemotherapy.
• Patients with evidence of complete or near complete response criteria after completion of neoadjuvant treatment (approximately 8 weeks later). Response criteria should be based on digital rectal examination, flexible rectoscopy and MRI.

You may not qualify if…

• Evidence of distant metastases.

Where it is running

• Hospital General Universitario de Elche — Elche, Alicante, Spain (enrolling)

Full record on ClinicalTrials.gov

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