Post Acute Pancreatitis Pancreatic Exocrine Insufficiency

Completed

Conditions studied: Acute Pancreatitis

In brief

This study is a proposed a comprehensive prospective assessment of exocrine pancreatic insufficiency (EPI), nutritional status, and quality of life (QOL) during the early re-feeding phase, at 3 months, and 12 months following an AP attack.

Key facts

Study ID

NCT03063398

Run by

Ohio State University

People needed

196

Starts

2017-06-21

Expected to finish

2024-06-30

Last updated by the study team

2024-07-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Men and women, at least 18 years of age, admitted at the University of Pittsburgh Medical Center with an AP attack defined as the presence of 2 or more of the following criteria:
• Abdominal pain consistent with the disease,
• Serum amylase and/or lipase greater than three times the upper limit of normal, and or
• Characteristic findings from abdominal imaging (i.e. demonstrating pancreatic edema, peripancreatic fat stranding or complications or acute pancreatitis)

You may not qualify if…

• Known or newly diagnosed chronic pancreatitis based on cross sectional imaging findings
• Pre-existing exocrine pancreatic insufficiency (meaning EPI present before the onset of AP; development of EPI during early refeeding is not an exclusion criterion)
• History of gastric or pancreatic resection
• History of small bowel disease (celiac disease, or Crohn's disease)
• History of pancreatic malignancy
• History of gastroparesis
• History of cystic fibrosis

Where it is running

• Johns Hopkins Medical Institutions — Baltimore, Maryland, United States
• The Ohio State University — Columbus, Ohio, United States
• UPMC Presbyterian — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.