Comparison of Obturator Nerve Blockade and Neuromuscular Blockade

Completed · Phase 4

Conditions studied: Cancer of Bladder

In brief

Patients diagnosed with posterolateral bladder tumors will be invited to participate in the study. Subjects will be randomized to receive an ultrasound-guided obturator block or a neuromuscular blocking agent after the induction of general anesthesia in an attempt to block the obturator reflex during surgery.

Key facts

Study ID

NCT03063255

Run by

University of Florida

People needed

60

Starts

2017-04-25

Expected to finish

2019-09-19

Last updated by the study team

2021-03-24

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients ≥ 18 years of age
• Planned TURBT for unilateral or bilateral posterolateral bladder tumors
• Ability to understand and provide informed consent

You may not qualify if…

• Patient refusal or inability to provide informed consent
• True allergy, not sensitivity, to local anesthetics
• True allergy, not sensitivity, Propofol
• True allergy, not sensitivity, general anesthetic agents
• Pregnancy
• Severe hepatic impairment
• Evidence of infection at or near the proposed needle insertion site
• Any sensorimotor deficit of the lower extremity, whether acute or chronic
• Inability to walk without assistance
• Lower extremity joint replacement surgery in the preceding six months

Where it is running

• Malcom Randall VA Medical Center — Gainesville, Florida, United States

Full record on ClinicalTrials.gov

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