Light Therapy as Treatment for Fatigue in Multiple Sclerosis
Completed · Not applicable
Conditions studied: Multiple Sclerosis, Relapsing-Remitting
In brief
This prospective study will randomize 1:1 people living with multiple sclerosis-associated fatigue to one of two spectra of light therapy. Each participant will be asked to use the light box twice daily at home or at the workplace at preset hours during the day for a total of four weeks. Participants will be asked to record their fatigue on standard measurement scales before, during, and after the use of the light therapy box. The investigators anticipate a reduction in self-reported fatigue following the use of the light box therapy of a particular spectrum of light among people living with multiple sclerosis.
Key facts
- Study ID
- NCT03060759
- Run by
- Massachusetts General Hospital
- People needed
- 35
- Starts
- 2017-04-01
- Expected to finish
- 2019-11-04
- Last updated by the study team
- 2020-05-13
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Relapsing remitting Multiple Sclerosis based on the McDonald Criteria (2010)
- Over 18 years old
- Presence of fatigue defined as FSS over 36
You may not qualify if…
- A change in an anti-depressant up to 4 weeks prior to study screening
- A change in fatigue medication regime or MS disease modifying therapy up to 4 weeks prior to study screening
- Shift work
- Use of photosensitizing medication
- Presence of eye trauma or acute optic neuritis within the preceding 3 months
- History of traumatic brain injury
- Probable (untreated) sleep apnea based on Berlin questionnaire
- Significant anemia
- History of mania
- MS relapse in the preceding four weeks
- Current pregnancy
- Known light sensitivity
- Other complicating illness preventing study completion.
Where it is running
- Massachusetts General Hospital — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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