PDL and Fractional Photothermolysis for Postsurgical Scars

Running, not enrolling · Not applicable

Conditions studied: Scar

In brief

This is a two part study to evaluate the efficacy of early combined PDL (pulsed dye laser) and fractional photothermolysis in the cosmetic improvement of post surgical scars.All subjects will be offered at the time of the dermatologic procedure, an option to treat the post surgical scars with early combined PDL and fractional photothermolysis. Part A is a non-randomized study design and subjects will have the choice of whether or not they will receive treatment. In part B, subjects will be randomized in a 2:1 treatment vs. control design. The experimental group will have a total of 6 visits: 1 standard of care suture removal visit, 3 treatment visits and 2 follow up visits. The control group will have 3 visits: 1 standard of care suture removal visit and 2 follow up visits. Subjects currently living in the Chicago metropolitan area and meet inclusion/exclusion criteria will be considered for enrollment. This study is a pilot study designed to determine feasibility of this procedure.

Key facts

Study ID

NCT03057964

Run by

Northwestern University

People needed

76

Starts

2017-03-01

Expected to finish

2027-12-01

Last updated by the study team

2026-07-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Males or females ≥ 18 years old
• Fitzpatrick skin types I-VI
• Subjects are in good health as judged by the investigator.
• Subjects who have received dermatologic surgery procedure of the trunk or extremities closed with complex primary closure with subcuticular running suture removed at 2-3 weeks.
• Subjects applying topical retinoids, must discontinue one week prior to treatment.
• Subjects who are willing and have the ability to understand and provide informed consent for participation in the study and are able to communicate with the investigator.

You may not qualify if…

• History of recurrent facial or labial herpes simplex infection
• Subjects applying topical retinoids, must discontinue one week prior to treatment.
• Subjects with a history of hypertrophic scars or keloids
• Pregnant or breast feeding
• Uncooperative patients or patients with neurological disorders who are incapable of following directions or who are predictably unwilling to return for follow-up examinations.
• Subjects who are unable to understand the protocol or give informed consent.
• Subjects who in the opinion of the investigator are likely to have exaggerated scarring with laser treatments.

Where it is running

• Northwestern University Feinberg School of Medicine, Department of Dermatology — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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