Metoclopramide for Post-Traumatic Headache. A Pilot Study

Completed · Phase 1/Phase 2

Conditions studied: Post-Traumatic Headache

In brief

Post-traumatic headache is common. We are determining short and longer-term outcomes among patients treated for post-traumatic headache with IV metoclopramide.

Key facts

Study ID

NCT03056352

Run by

Montefiore Medical Center

People needed

21

Starts

2017-03-01

Expected to finish

2017-08-15

Last updated by the study team

2018-07-31

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Traumatic injury to the head has occurred
• Headache has developed within 7 days of injury to the head
• Headache is not better accounted for by another diagnosis (eg, previous history of migraine or tension-type headache)
• The headache must be rated as moderate or severe in intensity at the time of initial evaluation.
• The plan of the attending emergency physician must include treatment with parenteral metoclopramide.

You may not qualify if…

• Patients will be excluded if more than ten days have elapsed since the head trauma, if the headache has already been treated with an anti-dopaminergic medication, or for medication contra-indications including pheochromocytoma, seizure disorder, Parkinson's disease, use of monoamine oxidase inhibitors, and use of anti-rejection transplant medications. Patients will not be excluded for pregnancy or breast-feeding.

Where it is running

• Montefiore Medical Center — The Bronx, New York, United States

Full record on ClinicalTrials.gov

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