Gene Expression in Hyperparathyroidism

Stopped early

Conditions studied: Parathyroid Disease, Hyperparathyroidism

In brief

Objectives: 1. To better define the differences in molecular genetics of parathyroid tumors in patients with MEN1, single gland parathyroid disease in patients less than 50 years old and single gland disease in patients greater than 50 years old. 2. To better define the incidence of HRPT2 mutation in young patients with primary hyperparathyroidism and determine whether routine testing in these patients is indicated.

Key facts

Study ID

NCT03044600

Run by

M.D. Anderson Cancer Center

People needed

22

Starts

2012-11-07

Expected to finish

2017-10-18

Last updated by the study team

2019-05-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All patients previously enrolled in parathyroid tissue banking under protocol Lab08-0034.
• For the subgroup designated for HRPT2 mutation testing:
• Patients with primary hyperparathyroidism who are younger than 50 years of age and have tested negative for MEN1, between January 1, 1980 and the present.

You may not qualify if…

• N/A

Where it is running

• University of Texas MD Anderson Cancer Center — Houston, Texas, United States

Full record on ClinicalTrials.gov

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