Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis

Recruiting now

Conditions studied: Pseudomonas Infections, Pseudomonas Septicemia, Pseudomonas; Pneumonia, Pseudomonal Bacteraemia, Pseudomonas Urinary Tract Infection, Pseudomonas Gastrointestinal Tract Infection, Sepsis, Sepsis, Severe, Critically Ill

In brief

The present study focuses on patients with Pseudomonas aeruginosa (PSA) sepsis. The aim of the present study is to find out whether the M1 (pro-inflammatory) or M2 (anti-inflammatory) phenotype predominates in blood monocytes in critically ill patients with PSA-sepsis, and whether the severity of sepsis and outcome is associated with distinct monocyte phenotype and function.

Key facts

Study ID

NCT03044223

Run by

University of Ulm

People needed

100

Starts

2014-08-01

Expected to finish

2026-12-01

Last updated by the study team

2024-01-17

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• age > 18 years
• critically ill patients with sepsis
• microbiologically proven infection with Pseudomonas aeruginosa

You may not qualify if…

• life expectancy < 24 hours
• participation in other studies

Where it is running

• Clinic of Anesthesiology — Ulm, Germany (enrolling)

Full record on ClinicalTrials.gov

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