Cangrelor in ST-Elevation Myocardial Infarction to Decrease Infarct Size

Stopped early · Phase 4

Conditions studied: STEMI - ST Elevation Myocardial Infarction

In brief

This study evaluates differences in the extent of myocardial necrosis noted by cardiac MRI in patients with ST-elevation myocardial infarction randomized to receive cangrelor during their percutaneous coronary intervention and compares them to patients randomized to not receive cangrelor.

Key facts

Study ID

NCT03043274

Run by

Khaled Ziada, MD

People needed

23

Starts

2017-01-01

Expected to finish

2019-05-01

Last updated by the study team

2020-06-30

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with an acute STEMI with the University of Kentucky as the institution of presentation with plans for PCI
• English-speaking

You may not qualify if…

• Pregnant patients
• Prisoners
• Patients who are unable to provide his/her own consent
• Patients with a prior history of myocardial infarction
• Patients who have received thrombolytics
• Patients on systemic anticoagulation
• Patients who are hemodynamically unstable with evidence of shock
• Patients who are mechanically intubated
• Patients with devices not MRI compatible
• Patients with chronic kidney disease, glomerular filtration rate less than 30
• Patients who are already on dual antiplatelet therapy

Where it is running

• University of Kentucky — Lexington, Kentucky, United States

Full record on ClinicalTrials.gov

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