Care Optimization Through Patient and Hospital Engagement Clinical Trial for Heart Failure

Completed · Not applicable

Conditions studied: Heart Failure

In brief

CONNECT-HF is a large-scale, pragmatic, cluster-randomized clinical trial to evaluate the effect of a customized, multifaceted, health system-level quality-improvement (QI) program compared with usual care on heart failure (HF) outcomes and HF quality-of-care metrics.

Key facts

Study ID

NCT03035474

Run by

Duke University

People needed

5749

Starts

2017-04-21

Expected to finish

2020-12-31

Last updated by the study team

2021-01-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years
• Acute HF as a primary cause of hospitalization
• Hospitalizations for acute HF will be determined by local clinician-investigators but should include the following:
• Symptoms (eg, dyspnea, fatigue), signs (eg, elevated jugular venous pressure, peripheral edema), or laboratory/imaging evidence of HF (eg, pulmonary congestion on chest x-ray, elevated natriuretic peptide levels) during the hospitalization and
• Treatments aimed at acute HF (eg, intravenous diuretics, vasodilators, or inotropes)
• LVEF ≤ 40% based on last local measurement using echocardiography, multigated acquisition scan, computed tomography (CT) scanning, magnetic resonance imaging, or ventricular angiography
• Planned discharge to home or other supported care facility where patients are individually responsible for medication management

You may not qualify if…

• Prior heart transplant or current/planned left ventricular assistance device
• Chronic kidney disease requiring dialysis
• Terminal illness other than HF, such as malignancy, or with a life expectancy of less than 1 year as determined by the enrolling clinician-investigator
• Unable to participate in longitudinal follow-up, such as plans to move outside the US in the following year

Where it is running

• Providence Alaska Medical Center — Anchorage, Alaska, United States
• Sparks Regional Medical Center — Fort Smith, Arkansas, United States
• Arkansas Heart Hospital and Clinics — Little Rock, Arkansas, United States
• San Gorgonio Memorial Hospital — Banning, California, United States
• Memorial Medical Center — Modesto, California, United States
• Dignity Health Sequoia Hospital — Redwood City, California, United States
• Riverside Community Hospital — Riverside, California, United States
• Sutter Medical Center — Sacramento, California, United States
• Stanford University — Stanford, California, United States
• Torrance Memorial Medical Center — Torrance, California, United States
• University of Colorado Hospital — Aurora, Colorado, United States
• UC Health Memorial — Colorado Springs, Colorado, United States
• Northern Colorado Medical Center — Greeley, Colorado, United States
• Stamford Hospital — Stamford, Connecticut, United States
• JFK Medical Center — Atlantis, Florida, United States
• Manatee Memorial Hospital — Bradenton, Florida, United States
• Blake Medical Center — Bradenton, Florida, United States
• Broward Health Imperial Point — Fort Lauderdale, Florida, United States
• Holy Cross Hospital — Fort Lauderdale, Florida, United States
• Broward Health Medical Center — Fort Lauderdale, Florida, United States
• Mayo Clinic Florida — Jacksonville, Florida, United States
• Orlando Health — Orlando, Florida, United States
• Cardiovascular Institute of Northwest Florida — Panama City, Florida, United States
• Baptist Hospital — Pensacola, Florida, United States
• University of Alabama Hospital — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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