High Intensity Interval Training in Heart Failure
Withdrawn before enrolling · Not applicable
Conditions studied: Heart Failure, Physical Activity
In brief
The investigators will assess the efficacy and safety of utilizing high-intensity interval training in stable heart failure patients on functional outcomes. Specifically, an assessment of baseline peak oxygen uptake and peak cardiac output will be assessed before and 8 weeks after intense interval training. Measurements of quality of life will be assessed before and after training as well as the number of arrhythmic events before and after training. The control group will be a group that will follow a moderate exercise training protocol over a similar period.
Key facts
- Study ID
- NCT03032081
- Run by
- Georgia State University
- People needed
- 0
- Starts
- 2017-03-02
- Expected to finish
- 2018-07-01
- Last updated by the study team
- 2017-08-23
Who can join
Age: 40 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Stable, chronic heart failure with a left ventricular ejection fraction of 20 to 40%.
- New York Heart Association (NYHA) class I to III symptoms with treatment that includes beta-blocker and angiotensin-converting enzyme (ACE) inhibitor and angiotensin receptor blocker (ARB) Therapy for at least eight weeks prior to exercise training if ejection fraction is < 35%.
- No recent major cardiovascular hospitalizations or procedures within the previous three months.
- Age 40-65 years
- Aerobic capacity ≥ 12 mL/kg/min.
- Subjects with an implantable cardioverter defibrillator (ICD) are also included.
- Subjects with right ventricular systolic pressure ≤ 60 mmHg at rest.
You may not qualify if…
- Inability to exercise (orthopedic or neurological problems).
- History of seizure disorders.
- History of atrial fibrillation or ventricular tachycardia in the past 3 months.
- Implantable cardioverter defibrillator shocks due to atrial fibrillation or ventricular fibrillation within the past 3 months.
- Presence of pacemaker.
- Uncontrolled diabetes mellitus.
- Diabetic insulin pump.
- Uncontrolled hypertension.
- Renal insufficiency (creatinine: > 2.5 mg/dl).
- Severe left ventricular hypertrophy (> 1.8 cm wall thickness) or dynamic left ventricular outflow tract obstruction.
- Greater than mild degree of valve stenosis or presence of an artificial heart valve.
- Drug addiction.
- Not being able to read and understand the consent form.
- Signs of unreliableness.
Where it is running
- Grady Memorial Hospital — Atlanta, Georgia, United States
Full record on ClinicalTrials.gov
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