Propranolol for Treating Fibromyalgia Pain
Stopped early · Phase 1 · Has a placebo group
Conditions studied: Fibromyalgia Pain
In brief
The purpose of the study to evaluate the feasibility of using low dose propranolol for people with fibromyalgia.
Key facts
- Study ID
- NCT03029845
- Run by
- University of Utah
- People needed
- 15
- Starts
- 2017-01-01
- Expected to finish
- 2018-07-01
- Last updated by the study team
- 2018-08-23
Who can join
Age: 18 and older, up to 65. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Females with fibromyalgia (both meeting 1990 American College of Rheumatology (ACR) FMS criteria and 2010 ACR FMS criteria) age 18-65 with at least 1 year of symptoms and sedentary (exercising less than 120 min per week).
You may not qualify if…
- General Health Criteria:
- Uncontrolled/unstable illnesses (physician diagnosed, self-report)
- Pregnancy or planning to be pregnant in the next year
- Having Asthma requiring medication treatment including inhaler
- Type I diabetes or Type II diabetes requiring medical therapy that can lead to hypoglycemia
- Having acute pain or neuropathic pain
- Participation in exercise or psychological treatment studies in the past 2 years
- Having known serious psychopathology: Psychosis, history of inpatient psychiatric admission in the past year, active suicidal intent, history of self-injurious behaviors in the past year, history of recreational IV drug use, substance abuse history in the past year)
- Cardiovascular Criteria:
- Having known cardiovascular diseases (self-report, physician diagnosed)
- Pacemaker
- Bradycardia (resting heartrate of less than 55 bpm)
- Resting diastolic BP < 55 mmHG or systolic BP<100 mmHG
- ECG showing prolonged PR interval > .2 sec
- ECG showing irregular PR interval
- ECG showing incongruence between P wave and QRS
- Medication Criteria
- Allergy or intolerance of beta blockers
- Current use of the following drugs:
- Antihypertensive drugs
- Neuroleptics
- Monoamine oxidase inhibitors
- Tizanidine
- Amphetamine-based medications
- Bupropion
Where it is running
- University of Utah — Salt Lake City, Utah, United States
Full record on ClinicalTrials.gov
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