Simulated-altitude to Optimize Aerobic Exercise Among Breast Cancer Survivors With Limited Mobility
Completed · Not applicable
Conditions studied: Obesity, Breast Cancer
In brief
The study will evaluate the utility of hypoxic exercise training to improve cardiovascular and metabolic health among obese breast cancer survivors. While participants exercise, a lower fraction of inspired oxygen will be used to simulate a higher altitude. This approach removes the mechanical strain needed to sustain moderate-to-vigorous exercise intensity which is believed to support exercise tolerance. Participants are randomized to either the treatment (walking+simulated-altitude) or control (walking under normoxic conditions).
Key facts
- Study ID
- NCT03029182
- Run by
- University of Alabama at Birmingham
- People needed
- 15
- Starts
- 2016-10-01
- Expected to finish
- 2018-04-01
- Last updated by the study team
- 2018-05-14
Who can join
Age: 18 and older, up to 70. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Physician's medical clearance for participation
- English-speaking women
- 18-70 years of age with a history of Stage 0-III breast cancer
- Preferred walking speed of less than 2.9 mph as measured by a timed 10 meter walk test (to be performed on-site after consent during preliminary screening) "OR" the inability to complete a 6-minute walk without stopping (to be performed on-site after consent during preliminary screening)
- Body mass index between 30-45 kg/m2
- ≥1 year post-treatment and not currently receiving or planning to receive chemo/radiation therapies
- Not participating in a structured exercise routine
- In the previous 6 months, not engaging in (on average) ≥60 minutes of moderate or ≥30 minutes of vigorous physical activity per week.
You may not qualify if…
- Males
- Dementia
- Medical, psychological, and/or social characteristics that may interfere with the ability to fully participate in the proposed study activities/assessments (e.g., psychosis, schizophrenia)
- Contraindication to participate in regular exercise training
- Unwilling to complete prescribed exercise
- Inability to walk
- Pregnant
- Resting oxygen saturation via pulse oximetry below 90%
- Using home oxygen therapy
Where it is running
- University of Alabama at Birmingham — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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