TPI Medication Comparison - Ketorolac, Lidocaine, or Dexamethasone

Stopped early · Phase 4

Conditions studied: Myofascial Pain

In brief

Hypothesis The main hypothesis of this study is that anti-inflammatory medications (ketorolac or dexamethasone) will provide longer-lasting and greater pain relief than just lidocaine in trigger point injections where a local twitch response is evoked at the time of the injection. Purpose/Specific Aims The primary objective of this study is to compare the efficacy of three substances used in TPIs with a LTR identified at the time of the injection: a CS (dexamethasone), a NSAID (ketorolac), or only a local anesthetic (lidocaine).

Key facts

Study ID

NCT03028012

Run by

University of Utah

People needed

10

Starts

2017-05-02

Expected to finish

2019-05-01

Last updated by the study team

2020-11-18

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Men or women age 18 or over
• At least one active trigger point

You may not qualify if…

• Allergy or contraindication to any NSAID, CS, or local anesthetic
• Receiving anticoagulant medication
• History of bleeding disorder
• Pregnant or breast feeding women
• Gastrointestinal ulceration
• Pre-existing renal disease
• Pre-existing congestive heart failure
• Diabetes mellitus
• Prior myocardial infarction or stroke
• Fibromyalgia

Where it is running

• University of Utah Orthopaedic Center — Salt Lake City, Utah, United States

Full record on ClinicalTrials.gov

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