Sex and Age Ultrasound Response to Differential Jugular Vein Pressure

Completed · Not applicable

Conditions studied: Concussion, Mild

In brief

Clinical trials have suggested that this device is effective in mitigating changes in brain structure and function in athlete populations. The purpose of the current study is to measure the response of the jugular vein to various pressures applied by a generic compression device across various ages and gender. The relative jugular vein response will be measured using ultrasound.

Key facts

Study ID

NCT03017937

Run by

Children's Hospital Medical Center, Cincinnati

People needed

155

Starts

2016-11-01

Expected to finish

2019-06-01

Last updated by the study team

2020-11-17

Who can join

Age: 7 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Normal healthy volunteer aged 7-60
• Able to provide written consent
• Able to tolerate hypercapnia for 1-2 minutes

You may not qualify if…

• Unable to provide written consent
• History of neurological deficits, previous cerebral infarction, or severe head trauma as indicated through pre-season screening:
• Medical contraindications to restriction of venous outflow via the internal jugular veins (known increased intracerebral pressure, metabolic acidosis or alkalosis)
• Glaucoma (Narrow Angle or Normal Tension)
• Hydrocephalus
• Recent penetrating brain trauma (within 6 months)
• Known carotid hypersensitivity
• Known increased intracranial pressure
• Central vein thrombosis
• Any known airway obstruction
• Any known seizure disorder

Where it is running

• Cincinnati Childrens Hospital Medical Center — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

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