Novel Listeria Vectors Secreting Gut Flora-Altering Agents to Prevent Colon Cancer and Treat Colitis

Withdrawn before enrolling

Conditions studied: Colon Cancer, Colitis

In brief

This is a simple tissue collection study with no therapeutic intent. Colon tissues will be taken from standard of care procedures. Tissues will be tested for their functions, expression of immune co-signaling molecules and reactions to transduction with recombinant Listeria vectors to assess effects on expression of B7-H1 and cytokines.

Key facts

Study ID

NCT03014284

Run by

The University of Texas Health Science Center at San Antonio

People needed

0

Starts

2017-01-20

Expected to finish

2018-09-12

Last updated by the study team

2018-09-17

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Able to provide informed consent (or have consent provided through a guardian)
• No immune-modulating drug use during study or within 30 days prior to enrollment
• Having colon material collected as part of standard of care

You may not qualify if…

• Unable to provide informed consent (or have consent provided through a guardian)
• Not having colon material collected as part of standard of care

Where it is running

• Cancer Therapy & Research Center at UTHSCSA — San Antonio, Texas, United States

Full record on ClinicalTrials.gov

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