Biomarkers for Muscle Function and Aging in Chronic HIV Infection
Status unconfirmed
Conditions studied: HIV
In brief
MATCH is an observation study of HIV-infected adults on effective antiretroviral therapy (ART) and demographically matched uninfected adults to evaluate muscle and aging.
Key facts
- Study ID
- NCT03011957
- Run by
- Brigham and Women's Hospital
- People needed
- 160
- Starts
- 2015-02-01
- Expected to finish
- 2020-02-01
- Last updated by the study team
- 2018-01-18
Who can join
Age: 50 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Group 1: HIV positive subjects
- HIV positive
- English speaking
- 50-65 years old
- On Antiretroviral therapy and an HIV viral load below 200 copies/ml
- CD4 equal to or greater than 350 cells/mm3
- Postmenopausal (women)
- Lower extremity mobility sufficient to participate in functional assessment.
- Group 2: HIV negative subjects Inclusion Criteria for Group 2 subjects
- English speaking
- 50-65 years old
- Negative for HIV (based on an HIV antibody test at Study Visit 1)
- Matched to Group 1 for sex (50% W, 50% M) and age (50 - 65yo)
- Postmenopausal (women)
- Lower extremity mobility sufficient to participate in functional assessment.
You may not qualify if…
- Exclusion Criteria for Group 1 Subjects
- Acute or serious illness within 60 days prior to entry
- Use of pharmacologic doses of corticosteroids in the past 6 months.
- Use of anabolic therapy in the past 6 months.
- Lower extremity mobility insufficient to participate in functional assessment.
- Current use (last 30 days) of anticoagulants or known bleeding disorder.
- Exclusion Criteria for Group 2 subjects
- Acute or serious illness within 60 days prior to entry
- Use of pharmacologic doses of corticosteroids in the past 6 months
- Use of anabolic therapy in the past 6 months
- Lower extremity mobility insufficient to participate in functional assessment
- Current use (last 30 days) of anticoagulants or known bleeding disorder.
Where it is running
- Brigham and Women's Hospital — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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