Polyethylene Glycol Cleansing in Patients at High Risk for Poor Bowel Preparation

Status unconfirmed · Not applicable

Conditions studied: Colonoscopy

In brief

The aim of this randomized trial is to compare the proportion of patients achieving an adequate bowel preparation after a 1-day split-dose 4-liter PEG-based bowel preparation regimen (Golytely, Braintree Laboratory Inc, MA, USA) vs. the same regimen given on 2 consecutive days in a population identified as high risk for an inadequate bowel preparation. 2\. Research Design: This study is a single-center prospective randomized study at the West Haven VAMC. 3\. Methodology: 1. Primary endpoint: Adequate bowel preparation as defined by a Boston Bowel Preparation Scale (BBPS) score of 2 or 3 (on scale of 0-3) in all 3 colon segments (left, transverse, and right). 2. Secondary endpoints: Adenoma detection rate, polyp detection rate, sessile serrated polyp/adenoma detection rate, patient tolerability of preparation using the validated Mayo clinic bowel prep tolerability questionnaire, adverse events potentially related to bowel preparation Patients scheduled for routine outpatient colonoscopy will be eligible if they are at high risk for poor bowel preparation,

Key facts

Study ID

NCT03011788

Run by

VA Connecticut Healthcare System

People needed

270

Starts

2017-01-01

Expected to finish

2021-12-01

Last updated by the study team

2019-12-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Risk factors that increase likelihood of poor bowel prep

You may not qualify if…

• prior colon resection
• Women of child bearing age

Where it is running

• West Have VAMC — West Haven, Connecticut, United States (enrolling)

Full record on ClinicalTrials.gov

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