Lorcaserin in the Treatment of Cocaine Use Disorder

Completed · Phase 2 · Has a placebo group

Conditions studied: Cocaine-Related Disorders

In brief

The objective of this study is to evaluate the efficacy and safety of lorcaserin in the treatment of cocaine use disorder.

Key facts

Study ID

NCT03007394

Run by

National Institute on Drug Abuse (NIDA)

People needed

272

Starts

2017-12-19

Expected to finish

2019-12-01

Last updated by the study team

2020-08-05

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Has a DSM-5 diagnosis of current cocaine use disorder as verified by the Structured Clinical Interview for DSM-5
• Is seeking treatment for cocaine use disorder
• Is able to understand and provide written informed consent
• Has used cocaine on at least 1 day in the last 30 days prior to screening
• Has completed all psychological assessments and procedures during the screening period
• If female, not pregnant, lactating, unable to conceive OR must agree to use an acceptable method of birth control
• Has a total body weight greater than 110 pounds and body mass index greater than 20

You may not qualify if…

• Contact site for more information

Where it is running

• Pacific Treatment and Research Center — La Jolla, California, United States
• Matrix Institute on Addictions — Los Angeles, California, United States
• Pharmacology Research Institute — Newport Beach, California, United States
• George Washington University — Washington D.C., District of Columbia, United States
• Meridien Research — Lakeland, Florida, United States
• Behavioral Clinical Research, Inc. — North Miami, Florida, United States
• Boston University School of Medicine — Boston, Massachusetts, United States
• Altea Research Institute — Las Vegas, Nevada, United States
• Hassman Research Institute — Berlin, New Jersey, United States
• Neuro-Behavioral Clinical Research Inc. — Canton, Ohio, United States
• University of Cincinnati — Cincinnati, Ohio, United States
• CODA, Inc. — Portland, Oregon, United States

Full record on ClinicalTrials.gov

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