A Study to Test Combination Treatments in People With Advanced Renal Cell Carcinoma

Completed · Phase 2

Conditions studied: Advanced Cancer

In brief

The purpose of this study is to test the effectiveness and safety of various nivolumab combinations compared to nivolumab and ipilimumab in participants with advanced kidney cancer

Key facts

Study ID

NCT02996110

Run by

Bristol-Myers Squibb

People needed

182

Starts

2017-02-02

Expected to finish

2021-11-23

Last updated by the study team

2022-12-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Advanced Renal Cell Carcinoma
• Must have at least 1 lesion with measurable disease
• Life expectancy of at least 3 months
• Karnofsky Performance Status (KPS) must be =>70%

You may not qualify if…

• Patients/subjects with suspected or known central nervous system metastases unless adequately treated
• Patients/subjects with autoimmune disease
• Patients/subjects who need daily oxygen therapy
• Other protocol defined inclusion/exclusion criteria apply

Where it is running

• Local Institution - 0037 — New Haven, Connecticut, United States
• Local Institution — Tampa, Florida, United States
• Local Institution - 0031 — Augusta, Georgia, United States
• Local Institution - 0006 — Chicago, Illinois, United States
• Local Institution - 0007 — Baltimore, Maryland, United States
• Dana Farber Cancer Institute — Boston, Massachusetts, United States
• Massachusetts General Hospital — Boston, Massachusetts, United States
• Local Institution - 0011 — Detroit, Michigan, United States
• Local Institution - 0008 — St Louis, Missouri, United States
• Roswell Park Cancer Institute — Buffalo, New York, United States
• Local Institution - 0005 — New York, New York, United States
• Local Institution - 0043 — Charlotte, North Carolina, United States
• Local Institution - 0014 — Columbus, Ohio, United States
• Oregon Health & Science University — Portland, Oregon, United States
• Local Institution - 0002 — Allentown, Pennsylvania, United States
• Hollings Cancer Center — Charleston, South Carolina, United States
• Local Institution - 0025 — Nashville, Tennessee, United States
• Ut Southwestern Medical Center — Dallas, Texas, United States
• Local Institution - 0024 — Charlottesville, Virginia, United States
• University of Washington - Seattle Cancer Care Alliance — Seattle, Washington, United States
• Local Institution - 0032 — Westmead, New South Wales, Australia
• Monash Medical Centre Clayton — Bentleigh, Victoria, Australia
• Local Institution - 0044 — Linz, Upper Austria, Austria
• Local Institution - 0038 — Hamilton, Ontario, Canada
• Local Institution - 0029 — Oshawa, Ontario, Canada

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.