Targeted PET/CT and PET/MRI Imaging of Vascular Inflammation

Withdrawn before enrolling · Phase 2

Conditions studied: Aortic Aneurysm, Abdominal, Carotid Atherosclerosis

In brief

Stroke and abdominal aortic aneurysms (AAAs) are common and highly lethal vascular diseases. Angiogenesis and infiltration of inflammatory cells such as macrophages may cause stroke and AAAs. The purpose of this study is to test PET/CT and PET/MRI imaging to specifically detect those diseases using a new developed agent (18F-FPPRGD2) that can target angiogenesis and macrophages.

Key facts

Study ID

NCT02995642

Run by

Stanford University

People needed

0

Starts

2019-10-01

Expected to finish

2020-12-01

Last updated by the study team

2021-05-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Greater than 18 year-old at the time of radiotracer administration
• Provides written informed consent
• Patients diagnosed with either carotid artery stenosis or abdominal aortic aneurysms (AAAs) as identified in Vascular Surgery, in whom a surgical procedure is scheduled
• Able to remain still for duration of an imaging procedure (about one hour).

You may not qualify if…

• Less than 18 year-old at the time of radiotracer administration
• Unable to provide written informed consent
• Pregnant women
• Prior carotid or abdominal surgery
• History of radiation therapy to the neck and abdomen
• MRI contraindications (including ferromagnetic objects or devices).

Where it is running

• Stanford University — Stanford, California, United States

Full record on ClinicalTrials.gov

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