Podocyturia - Predictor of Renal Dysfunction in Fabry Nephropathy

Status unconfirmed

Conditions studied: Fabry Disease

In brief

In patients with Fabry disease, this research study explores the presence of podocytes in their urine as a potential non-invasive biomarker for baseline kidney disease; and explores changes in the quantity of podocytes in their urine over time as a predictor for kidney disease progression. To accomplish this, the investigators will evaluate the quantification of podocytes in the urine of Fabry disease patients at baseline and longitudinally over time. This study requires a single patient visit, during which the patient provides a urine specimen. The research team will then collect the patient's kidney function data proximate to the time of urine collection, and follow the patient's kidney function data longitudinally over the five years of this study by reviewing their medical charts. The study offers no interventions.

Key facts

Study ID

NCT02994303

Run by

University of Washington

People needed

58

Starts

2014-09-01

Expected to finish

2019-08-01

Last updated by the study team

2017-08-28

Who can join

Age: 0 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients must have been diagnosed with Fabry disease
• Patients must be between the ages of 1 day-90 years

You may not qualify if…

• Fabry disease patients who have had a renal transplant
• Fabry disease patients who are, or have been, subjects in any investigational drug study

Where it is running

• Emory University — Decatur, Georgia, United States (enrolling)
• University of Minnesota — Minneapolis, Minnesota, United States (enrolling)
• University of Washington — Seattle, Washington, United States (enrolling)

Full record on ClinicalTrials.gov

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