99Tc-MDP Treatment for Knee Osteoarthritis

Recruiting now · Not applicable

Conditions studied: Treatment Outcome

In brief

Osteoarthritis (OA) of knee is the most common form of arthritis in the world1e, and it has received growing attention in the society because of the increase of old age population, disabled people, and medical expenses from this disease. 99Tc-MDP is effective for rheumatoid arthritis. Therefore, the investigators try to investigate the effects of 99Tc-MDP treatment in patients with osteoarthritis of knee as compared with celecoxib.

Key facts

Study ID

NCT02993029

Run by

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

People needed

40

Starts

2017-09-01

Expected to finish

2027-12-30

Last updated by the study team

2026-04-28

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Participants with painful osteoarthritis;
• The standard uptake value (SUV) of OA related knee greater than 10 on 18F- sodium fluoride bone scan;
• Participants voluntarily participate in the trial, and signed the informed consent.

You may not qualify if…

• Knee joint replacement;
• Inflammatory arthritis or joint infection of knee;
• Nervous joint disease;
• Fracture of joint;
• Gout arthritis of the knee;
• Traumatic arthritis.

Where it is running

• Department of Nuclear Medicine, Tenth People's Hospital of Tongji University — Shanghai, Shanghai Municipality, China (enrolling)

Full record on ClinicalTrials.gov

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